EPAFinal Rule
Significant New Uses: Certain Chemical Substances (24-4.5e)
EnvironmentHealthcare
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Summary
The EPA is establishing new rules that require manufacturers to notify the agency before using certain chemicals in new or different ways than previously allowed. This gives the government a chance to review whether new uses of these chemicals might harm human health or the environment before products hit the market.
Key Points
- 1Manufacturers must get EPA approval before using regulated chemicals in new applications or industries
- 2The rule applies to specific chemical substances that the EPA has already identified as needing extra oversight
- 3Companies must submit detailed information about how they plan to use the chemicals and potential health and environmental risks
- 4The EPA has 45 days to review proposals and can reject, approve, or require changes before allowing the new use
- 5Violations can result in penalties, and companies cannot begin new uses until receiving EPA clearance
Key Dates
Published
November 4, 2025
This summary is for informational purposes only. It may not capture all nuances of the regulation. Always refer to the official text for authoritative information.
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